Exploring Novel Pyridine Carboxamide Derivatives as Urease Inhibitors: Synthesis, Molecular Docking, Kinetic Studies and ADME Profile

The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity. A series of pyridine carboxamide and carbothioamide derivative...

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书目详细资料
发表在:Pharmaceuticals
主要作者: Naseer A.; Osra F.A.; Awan A.N.; Imran A.; Hameed A.; Ali Shah S.A.; Iqbal J.; Zakaria Z.A.
格式: 文件
语言:English
出版: MDPI 2022
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140925076&doi=10.3390%2fph15101288&partnerID=40&md5=0f1a2f0c2a4e1cbca7be102f22639198