Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of β-Glucuronidase and in silico study
New benzimidazole analogues (1–18) were synthesized and characterized through different spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for β-glucuronidase inhibitory potential. All analogues showed varied degree of inhibitory potentials with IC50 values ran...
| Published in: | Arabian Journal of Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118560785&doi=10.1016%2fj.arabjc.2021.103505&partnerID=40&md5=86c929f9aa372ce6e6b7f7706329ed8a |