Synthesis, molecular docking study and thymidine phosphorylase inhibitory activity of 3-formylcoumarin derivatives
Thymidine phosphorylase (TP) over expression plays role in several pathological conditions, such as rheumatoid arthritis, chronic inflammatory diseases, psoriasis, and tumor angiogenesis. The inhibitor of this enzyme plays an important role in preventing the serious threat due to over expression of...
| 發表在: | Bioorganic Chemistry |
|---|---|
| 主要作者: | |
| 格式: | Article |
| 語言: | English |
| 出版: |
Academic Press Inc.
2018
|
| 在線閱讀: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042907693&doi=10.1016%2fj.bioorg.2018.02.028&partnerID=40&md5=9b94f4076ef61fbd0fc443e4ff380a96 |