Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies
Benzothiazole analogs (1-20) have been synthesized, characterized by EI-MS and 1H NMR, and evaluated for urease inhibition activity. All compounds showed excellent urease inhibitory potential varying from 1.4 ± 0.10 to 34.43 ± 2.10 μM when compared with standard thiourea (IC50 19.46 ± 1.20 μM). Amon...
| 发表在: | Bioorganic Chemistry |
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| 主要作者: | |
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Academic Press Inc.
2016
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| 在线阅读: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962360234&doi=10.1016%2fj.bioorg.2016.03.010&partnerID=40&md5=522911c76a6838509bcc4bf8327819dc |