The Effects of Different Solubilizing Agents on the Transport and Pharmacokinetic Profiles of Indomethacin: in vitro and in vivo Approach

The poor water solubility of new chemical entities (NCEs) discovered in pharmaceutical screening programs hampers their development and limits effective treatment delivery. Solubilizing agents offer a direct approach to increase solubility and oral bioavailability. This study employed indomethacin a...

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Bibliographic Details
Published in:SAINS MALAYSIANA
Main Authors: Zainuddin, Siti aisyah; Ab Hamid, Abdul latip; Rafandi, Aqila iman; Mohamad, Mashani; Hamid, Khuriah abdul; Khalid, Syed haroon
Format: Article
Language:English
Published: UNIV KEBANGSAAN MALAYSIA, FAC SCIENCE & TECHNOLOGY 2024
Subjects:
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-recordWOS:001367374600017