Identification of new structure of indol-3-acetyl-arylsulfonohydrazide as potent α-glucosidase and α-amylase inhibitors and molecular docking

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Identification of new structure of indol-3-acetyl-arylsulfonohydrazide as potent α-glucosidase and α-amylase inhibitors and molecular docking

Herein this work, indole analogs (1-16) were synthesized by treating 2-(1H-indol-3-yl)acetohydrazide with various aryl sulfonyl chloride in pyridine as solvent and screened for alpha-amylase and alpha-glucosidase inhibitory activity under positive control of standard drug acarbose (IC50 = 12.80 f 0....

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Bibliographic Details
Published in:	JOURNAL OF MOLECULAR STRUCTURE
Main Authors:	Taha, Muhammad; Rahim, Fazal; Zaman, Khalid; Imran, Syahrul; Khan, Khalid Mohammed; Shah, Syed Adnan Ali; Uddin, Nizam
Format:	Article
Language:	English
Published:	ELSEVIER 2025
Subjects:	Chemistry
Online Access:	https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-recordWOS:001363793300001

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