Identification of new structure of indol-3-acetyl-arylsulfonohydrazide as potent α-glucosidase and α-amylase inhibitors and molecular docking
Herein this work, indole analogs (1-16) were synthesized by treating 2-(1H-indol-3-yl)acetohydrazide with various aryl sulfonyl chloride in pyridine as solvent and screened for alpha-amylase and alpha-glucosidase inhibitory activity under positive control of standard drug acarbose (IC50 = 12.80 f 0....
| Published in: | JOURNAL OF MOLECULAR STRUCTURE |
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| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
ELSEVIER
2025
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| Subjects: | |
| Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-recordWOS:001363793300001 |