Synthesis, In Vitro Enzymatic Inhibition, and Molecular Modeling of Novel Piperazine-Based Bis-Schiff Base Derivatives as Promising Anti-urease Agents
The current study was aimed to synthesize piperazine-based bis-Schiff base derivatives (1-15) and were also screened in vitro for their inhibition against urease enzyme under the positive control of thiourea drug (IC50 value of 36.40 +/- 2.35 mu M). Among the tested analogs, the maximum potency was...
| Published in: | CHEMISTRYSELECT |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
WILEY-V C H VERLAG GMBH
2024
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| Subjects: | |
| Online Access: | https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001292248200001 |