Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents

Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents

Benzimidazole-based pyrrole/piperidine analogs (1-26) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (1-13) were screened in cholinesterase enzyme inhibit...

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Bibliographic Details
Published in:PHARMACEUTICALS
Main Authors: Tariq, Sundas; Rahim, Fazal; Ullah, Hayat; Sarfraz, Maliha; Hussain, Rafaqat; Khan, Shoaib; Khan, Misbah Ullah; Rehman, Wajid; Hussain, Amjad; Bhat, Mashooq Ahmad; Farooqi, Muhammad Kamran; Shah, Syed Adnan Ali; Iqbal, Naveed
Format: Article
Language:English
Published: MDPI 2024
Subjects:
Pharmacology & Pharmacy
Online Access:https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001210393500001

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https://www-webofscience-com.uitm.idm.oclc.org/wos/woscc/full-record/WOS:001210393500001

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