Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model

Introduction: The interaction between the T cell immune checkpoint proteins, the programmed death-1 (PD-1) receptor, and its ligand PD-L1 plays a crucial role in T cell suppression and the evasion of cancer cells from immune detection, thereby promoting tumour growth. Nivolumab, a PD-1 inhibitor, di...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Biomedical Research and Therapy
المؤلف الرئيسي: 2-s2.0-85219117249
التنسيق: مقال
اللغة:English
منشور في: BiomedPress 2024
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85219117249&doi=10.15419%2fbmrat.v11i2.864&partnerID=40&md5=97a6ca65123b9e18dce0e02386748aa6