2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

Pyridyl-benzimidazole analogues 1-11 with variable substituent on phenyl ring of phenacyl moiety were synthesized and evaluated for their urease inhibitory activity. The compounds exhibited urease inhibition with IC50 between 19.22 and 77.31 μM. Compounds 4 (IC50 = 19.22 ± 0.49 μM) showed a urease i...

詳細記述

書誌詳細
出版年:Medicinal Chemistry Research
第一著者: 2-s2.0-85027926278
フォーマット: 論文
言語:English
出版事項: Birkhauser Boston 2014
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027926278&doi=10.1007%2fs00044-014-1015-z&partnerID=40&md5=f027f7827a6f2f83909d4abaca7b6184