2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

Pyridyl-benzimidazole analogues 1-11 with variable substituent on phenyl ring of phenacyl moiety were synthesized and evaluated for their urease inhibitory activity. The compounds exhibited urease inhibition with IC50 between 19.22 and 77.31 μM. Compounds 4 (IC50 = 19.22 ± 0.49 μM) showed a urease i...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Medicinal Chemistry Research
المؤلف الرئيسي: 2-s2.0-85027926278
التنسيق: مقال
اللغة:English
منشور في: Birkhauser Boston 2014
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027926278&doi=10.1007%2fs00044-014-1015-z&partnerID=40&md5=f027f7827a6f2f83909d4abaca7b6184