Antileshmanial activities of synthetic substituted 2-phenyl-4-[phenylmethylidene]-1,3-oxazol-5(4H)-ones
Substituted 2-phenyl-4-[phenylmethylidene]-1,3-oxazol-5(4H)-ones 1-27 were evaluated for their activity against Leishmania major. Compounds 1-27 demonstrated in vitro antileishmanial activities with IC50 values between 28.9 - 69.05 μM, as compared to standard drug pentamidine (IC50 = 5.09 ± 0.04 μM)...
| Published in: | Journal of the Chemical Society of Pakistan |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Chemical Society of Pakistan
2015
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953334043&partnerID=40&md5=5c722873b2bfb3f6c5e69f55420e57ae |