Design of potent tyrosinase inhibiting N-arylated-4-yl-benzamides bearing 2-aminothiazole-triazole bi-heterocycles: mechanistic insight through enzyme inhibition, kinetics and computational studies

By using a convergent methodology, a unique series of N-arylated 4-yl-benzamides containing a bi-heterocyclic thiazole-triazole core was synthesized and the structures of these hybrid molecules, 9a-k, were corroborated through spectral analyses. The in vitro studies of these multi-functional molecul...

詳細記述

書誌詳細
出版年:RSC Advances
第一著者: 2-s2.0-85194053288
フォーマット: 論文
言語:English
出版事項: Royal Society of Chemistry 2024
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85194053288&doi=10.1039%2fd4ra01063a&partnerID=40&md5=b663ecb384fd7754b1d7b73422febbd8