Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up-to-date systematic review

• Published in: Biomedical Reports
• Main Author: 2-s2.0-85218266067
• Format: Article
• Language: English
• Published: Spandidos Publications 2025
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85218266067&doi=10.3892%2fbr.2024.1887&partnerID=40&md5=ebb41f5a041cb6f1e085e0d29c402846

Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were in vitro studies and 7 were in vivo or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti-inflammatory and anti-hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in-depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed. © 2024 Jusril et al. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License.