Synthesis, biological evaluation, and molecular docking study of novel 1,2,4-substituted triazoles as inhibitors of alzheimer’s disease
In order to explore effective acetyl and butyrylcholinesterase enzyme inhibitors, a library of fifteen synthetic 1,2,4-substituted triazoles (5–19) was established and characterized using IR and NMR spectroscopic techniques. Compounds 9 and 16 were found to be the most potent AChE (IC50 = 38.91 ± 0....
| Published in: | Journal of the Iranian Chemical Society |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media Deutschland GmbH
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136203736&doi=10.1007%2fs13738-022-02617-5&partnerID=40&md5=589609b1bc9159007cbde7e5a83479d0 |