Synthesis, biological evaluation, and molecular docking study of novel 1,2,4-substituted triazoles as inhibitors of alzheimer’s disease

In order to explore effective acetyl and butyrylcholinesterase enzyme inhibitors, a library of fifteen synthetic 1,2,4-substituted triazoles (5–19) was established and characterized using IR and NMR spectroscopic techniques. Compounds 9 and 16 were found to be the most potent AChE (IC50 = 38.91 ± 0....

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書目詳細資料
發表在:Journal of the Iranian Chemical Society
主要作者: 2-s2.0-85136203736
格式: Article
語言:English
出版: Springer Science and Business Media Deutschland GmbH 2022
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136203736&doi=10.1007%2fs13738-022-02617-5&partnerID=40&md5=589609b1bc9159007cbde7e5a83479d0