Synthesis and biological evaluation of novel coumarin derivatives bearing sulfonamide moiety as potent α-glucosidase inhibitors

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Synthesis and biological evaluation of novel coumarin derivatives bearing sulfonamide moiety as potent α-glucosidase inhibitors

Acarbose, miglitol and voglibose are α-glucosidase enzyme inhibitors that are clinically used to treat type-II diabetes mellitus. However, they are also associated with several adverse side effects. In this study, a series of sulfonamide-substituted coumarin was synthesised in a three-step reaction...

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Bibliographic Details
Published in:	Journal of the Iranian Chemical Society
Main Author:	Alsukor A.; Inayatsyah N.A.; Ridhwan M.J.M.; Kasim N.; Imran S.
Format:	Article
Language:	English
Published:	Springer Science and Business Media Deutschland GmbH 2025
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212866917&doi=10.1007%2fs13738-024-03143-2&partnerID=40&md5=83dfeff9edd9acadcfed5f1428722a6f

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