Exploration of the Out-of-Phase Phenomenon in Shake Flasks by CFD Calculations of Volumetric Power Input, kLa Value and Shear Rate at Elevated Viscosity

Culture broth with secreted macromolecules and culture broth of filamentous fungi showing disperse growth exhibit elevated viscosity, usually with shear-thinning flow behavior. High viscosity, however, poses a serious challenge in the production and research of these compounds and organisms. It comm...

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发表在:Biotechnology and Bioengineering
主要作者: Dinter C.; Gumprecht A.; Menze M.A.; Azizan A.; Hansen S.; Büchs J.
格式: 文件
语言:English
出版: John Wiley and Sons Inc 2025
在线阅读:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85210735708&doi=10.1002%2fbit.28892&partnerID=40&md5=4f733f750ae21a63c1a73c9e0d14ee25

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