Synthesis, In Vitro Enzymatic Inhibition, and Molecular Modeling of Novel Piperazine-Based Bis-Schiff Base Derivatives as Promising Anti-urease Agents
The current study was aimed to synthesize piperazine-based bis-Schiff base derivatives (1–15) and were also screened in vitro for their inhibition against urease enzyme under the positive control of thiourea drug (IC50 value of 36.40±2.35 μM). Among the tested analogs, the maximum potency was shown...
| Published in: | ChemistrySelect |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
John Wiley and Sons Inc
2024
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201207394&doi=10.1002%2fslct.202401106&partnerID=40&md5=64ac55dbff51d9106a24c7f2fdcf3e69 |