Role of TGF-β1/SMADs signalling pathway in resveratrol-induced reduction of extracellular matrix deposition by dexamethasone-treated human trabecular meshwork cells

Deposition of extracellular matrix (ECM) in the trabecular meshwork (TM) increases aqueous humour outflow resistance leading to elevation of intraocular pressure (IOP) in primary open-angle glaucoma, which remains the only modifiable risk factor. Resveratrol has been shown to counteract the steroid-...

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Bibliographic Details
Published in:Korean Journal of Physiology and Pharmacology
Main Author: Bakar A.S.A.; Razali N.; Agarwal R.; Iezhitsa I.; Perfilev M.A.; Vassiliev P.M.
Format: Article
Language:English
Published: Korean Physiological Soc. and Korean Soc. of Pharmacology 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198983678&doi=10.4196%2fkjpp.2024.28.4.345&partnerID=40&md5=69978ed7e604b9f53154f00092f8906f