Role of TGF-β1/SMADs signalling pathway in resveratrol-induced reduction of extracellular matrix deposition by dexamethasone-treated human trabecular meshwork cells
Deposition of extracellular matrix (ECM) in the trabecular meshwork (TM) increases aqueous humour outflow resistance leading to elevation of intraocular pressure (IOP) in primary open-angle glaucoma, which remains the only modifiable risk factor. Resveratrol has been shown to counteract the steroid-...
Published in: | Korean Journal of Physiology and Pharmacology |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Published: |
Korean Physiological Soc. and Korean Soc. of Pharmacology
2024
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198983678&doi=10.4196%2fkjpp.2024.28.4.345&partnerID=40&md5=69978ed7e604b9f53154f00092f8906f |