Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents

Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents

Benzimidazole-based pyrrole/piperidine analogs (1–26) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (1–13) were screened in cholinesterase enzyme inhibit...

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Published in:Pharmaceuticals
Main Author: Tariq S.; Rahim F.; Ullah H.; Sarfraz M.; Hussain R.; Khan S.; Khan M.U.; Rehman W.; Hussain A.; Bhat M.A.; Farooqi M.K.; Shah S.A.A.; Iqbal N.
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute (MDPI) 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191352219&doi=10.3390%2fph17040410&partnerID=40&md5=09d4ff1950e1e6bbb3f21b4c293d4720

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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191352219&doi=10.3390%2fph17040410&partnerID=40&md5=09d4ff1950e1e6bbb3f21b4c293d4720

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