Thymoquinone Reverses Homocysteine-Induced Endothelial Dysfunction via Inhibition of Endoplasmic Reticulum-Stress Induced Oxidative Stress Pathway

Hyperhomocysteinemia causes endoplasmic reticulum (ER) stress, which elevates reactive oxygen species (ROS) and induces endothelial dysfunction, the hallmark of cardiovascular diseases. Nigella sativa seeds contain thymoquinone (TQ), a cardioprotective bioactive component. Nevertheless, research on...

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Bibliographic Details
Published in:Sains Malaysiana
Main Author: Sofiullah S.S.M.; Murugan D.D.; Muid S.A.; Seng W.Y.; Zamakshshari N.H.; Gan Q.F.; Patrick M.; Azis N.A.; Sirasanagandla S.R.; Woon C.K.
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189096887&doi=10.17576%2fjsm-2024-5303-09&partnerID=40&md5=a96ed0193588d5fed2f5974c6fe7e992