Exploring diabetics II inhibitors based on benzodioxin derivatives, structure activity relationship, molecular docking and ADME property study

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Exploring diabetics II inhibitors based on benzodioxin derivatives, structure activity relationship, molecular docking and ADME property study

Enzyme inhibition is one of the main target for drug development against diabetes mellitus. In this regard we have conducted the synthesis of 1,4-benzodioxin bases Schiff bases (1–25). The α-amylase activities of these compounds (1–25) found in the range of 0.60 ± 0.01 to 19.80 ± 0.40 µM when compar...

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Bibliographic Details
Published in:	Journal of Molecular Structure
Main Author:	Al-Abdulbaqi M.A.; Taha M.; Rahim F.; Uddin I.; Uddin N.; Wadood A.; Haq S.; Iqbal N.; Khan K.M.; Ali shah S.A.; Ali M.
Format:	Article
Language:	English
Published:	Elsevier B.V. 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186449128&doi=10.1016%2fj.molstruc.2024.137797&partnerID=40&md5=4940362cfb4e8b3e3d782ecba19bcec9

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