Exploring diabetics II inhibitors based on benzodioxin derivatives, structure activity relationship, molecular docking and ADME property study
Enzyme inhibition is one of the main target for drug development against diabetes mellitus. In this regard we have conducted the synthesis of 1,4-benzodioxin bases Schiff bases (1–25). The α-amylase activities of these compounds (1–25) found in the range of 0.60 ± 0.01 to 19.80 ± 0.40 µM when compar...
| Published in: | Journal of Molecular Structure |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2024
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85186449128&doi=10.1016%2fj.molstruc.2024.137797&partnerID=40&md5=4940362cfb4e8b3e3d782ecba19bcec9 |