OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA
Testosterone is commonly used as a marker probe drug for CYP3A4 metabolic activity. Accurate measurement of its metabolite, 6β-hydroxytestosterone in cell culture media is very crucial. This study aimed to optimize solvent extraction method as well as to develop and validate HPLC analytical method f...
الحاوية / القاعدة: | Jurnal Teknologi |
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المؤلف الرئيسي: | Ridhwan M.J.M.; Mutalib N.A.; Latip N.A.; Rasol N.E.; Bakar S.I.A.; Ismail N.H. |
التنسيق: | مقال |
اللغة: | English |
منشور في: |
Penerbit UTM Press
2024
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الوصول للمادة أونلاين: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180491358&doi=10.11113%2fjurnalteknologi.v86.19861&partnerID=40&md5=6ad31eb7bba9e80a9c36ea1f3f437868 |
مواد مشابهة
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OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β- HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA
بواسطة: Ridhwan, وآخرون
منشور في: (2024) -
A Comprehensive Analysis of Human CYP3A4 Crystal Structures as a Potential Tool for Molecular Docking-Based Site of Metabolism and Enzyme Inhibition Studies
بواسطة: Ridhwan M.J.M.; Bakar S.I.A.; Latip N.A.; Ghani N.A.; Ismail N.H.
منشور في: (2022) -
A review of the recent development in self-healing rubbers and their quantification methods
بواسطة: Mohd Sani N.F.; Majid N.A.; Rehman A.; Hayeemasae N.; Radhakrishnan S.; Kulkarni M.B.; Khimi R.
منشور في: (2024) -
Site of Metabolism (SOM) Predictions for Centella asiatica and Orthosiphon stamineus Marker Compounds with CYP3A4 Using a Molecular Docking Approach
بواسطة: Ridhwan M.J.M.; Bakar S.I.A.; Ismail N.H.
منشور في: (2021) -
In Vitro Permeation Studies on Carvedilol Containing Dissolving Microarray Patches Quantified Using a Rapid and Simple HPLC-UV Analytical Method
بواسطة: Anjani Q.K.; Sabri A.H.B.; McGuckin M.B.; Li H.; Hamid K.A.; Donnelly R.F.
منشور في: (2022)