OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA
Testosterone is commonly used as a marker probe drug for CYP3A4 metabolic activity. Accurate measurement of its metabolite, 6β-hydroxytestosterone in cell culture media is very crucial. This study aimed to optimize solvent extraction method as well as to develop and validate HPLC analytical method f...
| Published in: | Jurnal Teknologi |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Penerbit UTM Press
2024
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180491358&doi=10.11113%2fjurnalteknologi.v86.19861&partnerID=40&md5=6ad31eb7bba9e80a9c36ea1f3f437868 |