OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA

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OPTIMIZATION OF DEPROTEINIZATION METHODS, HPLC METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF 6Β-HYDROXYTESTOSTERONE IN CELL CULTURE MEDIA

Testosterone is commonly used as a marker probe drug for CYP3A4 metabolic activity. Accurate measurement of its metabolite, 6β-hydroxytestosterone in cell culture media is very crucial. This study aimed to optimize solvent extraction method as well as to develop and validate HPLC analytical method f...

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Bibliographic Details
Published in:	Jurnal Teknologi
Main Author:	Ridhwan M.J.M.; Mutalib N.A.; Latip N.A.; Rasol N.E.; Bakar S.I.A.; Ismail N.H.
Format:	Article
Language:	English
Published:	Penerbit UTM Press 2024
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180491358&doi=10.11113%2fjurnalteknologi.v86.19861&partnerID=40&md5=6ad31eb7bba9e80a9c36ea1f3f437868

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