Inhibition of miR-96-5p alleviates intervertebral disc degeneration by regulating the peroxisome proliferator-activated receptor γ/nuclear factor-kappaB pathway

Background: Intervertebral disc degeneration (IDD) is the main pathogenesis of low back pain. MicroRNAs (miRNAs) have been found to exert regulatory function in IDD. This study aimed to investigate the effect and potential mechanism of miR-96-5p in IDD. Methods: In vitro cell model of IDD was establ...

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Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Author: Li X.; Hou Q.; Yuan W.; Zhan X.; Yuan H.
Format: Article
Language:English
Published: BioMed Central Ltd 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178235224&doi=10.1186%2fs13018-023-04412-1&partnerID=40&md5=16619e797d53861fd6c368e6d3fb51ca