Synthesis and biological evaluation of chromone derivatives against triple-negative breast cancer cells

This study described the bioactivity and the structure-activity relationship (SAR) of newly synthesized chromone derivatives against triple-negative breast cancer (TNBC) MDA-MB-231 cells. Among the compounds tested, C8 exerted a growth inhibitory effect on the TNBC-derived MDA-MB-231 cells with an I...

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Bibliographic Details
Published in:Medicinal Chemistry Research
Main Author: Islam R.; Yan M.P.; Yen K.P.; Rasol N.E.; Meng C.K.; Wai L.K.
Format: Article
Language:English
Published: Springer 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150307123&doi=10.1007%2fs00044-023-03048-4&partnerID=40&md5=81802d76a55467947e7bbaa52f7759ba