Synthesis, in vitro evaluation and molecular docking studies of hybrid 4-quinolinyl bearing 1,3,4-thiadiazole-2-amine as a new inhibitor of α-amylase and α-glucosidase
Synthesized scaffolds (1–19) of 4-quinolinyl based 1,3,4-thiadiazole-2-amine were evaluated in vitro for their α-amylase and α-glucosidase inhibition. All the newly synthesized scaffolds (1–19) were found to illustrate variable degree of inhibitory profile against α-amylase and α-glucosidase enzymes...
| Published in: | Journal of Molecular Structure |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2023
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149061065&doi=10.1016%2fj.molstruc.2023.135173&partnerID=40&md5=5fb2cb7640406975bc1c70bb2621b487 |