Insight parameter drug design for human β-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of α-keto-[1,2,4]-oxadiazoles
Dengue hemorrhagic fever (DHF) is severe dengue with a hallmark of vascular leakage. β-tryptase has been found to promote vascular leakage in DHF patients, which could be a potential target for DHF treatment. This study aims to develop a theoretical background for designing and selecting human β-try...
| Published in: | Journal of Biomolecular Structure and Dynamics |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Taylor and Francis Ltd.
2023
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147425113&doi=10.1080%2f07391102.2023.2171131&partnerID=40&md5=cdd31faf44bbc3df37fc57b16b524e87 |