New Quinoline Analogues: As Potential Diabetics Inhibitors and Molecular Docking Study

The 7-quinolinyl bearing 1,3,4-thiadiazole-2-amine analogues were synthesized (1–17) and based on the literature these analog were screened in vitro for their α-amylase and α-glucosidase inhibitory profile. All analogues showed moderate to good inhibitory potentials ranging between 0.80 ± 0.05 µM to...

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Bibliographic Details
Published in:Polycyclic Aromatic Compounds
Main Author: Taha M.; Salahuddin M.; Rahim F.; Imran S.; Hussain S.; Uddin N.; Khan K.M.
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2024
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147419609&doi=10.1080%2f10406638.2023.2169471&partnerID=40&md5=cb67df0ec9786609431d71c436d8e0ce