The NLRP3 Inflammasome in Age-Related Cerebral Small Vessel Disease Manifestations: Untying the Innate Immune Response Connection

In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSV...

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Bibliographic Details
Published in:Life
Main Author: Che Mohd Nassir C.M.N.; Damodaran T.; Ismail N.I.; Hashim S.; Jaffer U.; Hamid H.A.; Mehat M.Z.; Norazit A.; Mustapha M.
Format: Review
Language:English
Published: MDPI 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146757375&doi=10.3390%2flife13010216&partnerID=40&md5=1693831fd940f63055cc8305335440db