The effect of palm oil-derived tocotrienol-rich fraction in preserving normal retinal vascular diameter in streptozotocin-induced diabetic rats
Purpose: Angiogenesis in diabetic retinopathy (DR) is associated with increased retinal expression of angiopoietin-2 (Ang-2) and protein kinase C (PKC). Tocotrienol-rich fraction (TRF) has been shown to reduce the expression vascular endothelial growth factor (VEGF) in several experimental models. H...
Published in: | Graefe's Archive for Clinical and Experimental Ophthalmology |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media Deutschland GmbH
2023
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145898569&doi=10.1007%2fs00417-022-05965-3&partnerID=40&md5=0826fa4dfa2fe04f1c2b5bcb99688fa1 |