Benzoxazole based thiazole hybrid analogs: Synthesis, in vitro cholinesterase inhibition, and molecular docking studies

Acetylcholinesterase and butyrylcholinesterase enzymes are therapeutic target for Alzheimer disease and their inhibitors play a vital role for the treatment of this disease. A new series of benzoxazole based 1,3-thiazole hybrid scaffolds (1–20) were synthesized and assessed for acetylcholinesterase...

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Bibliographic Details
Published in:Computational Toxicology
Main Author: Hussain R.; Rahim F.; Rehman W.; Adnan Ali Shah S.; Khan S.; Khan I.; Rasheed L.; Imran S.; Wadood A.; Abdellatif M.H.
Format: Article
Language:English
Published: Elsevier B.V. 2023
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145589794&doi=10.1016%2fj.comtox.2022.100253&partnerID=40&md5=5178a43a1fd89db398ecfc193cf9a56b