New thiazole-based thiazolidinone derivatives: Synthesis, in vitro α-amylase, α-glucosidase activities and silico molecular docking study
A series of thiazole-based thiazolidinone derivatives (1-20) have been synthesized and evaluated against α-glucosidase and α-amylase enzymes. All derivatives showed good α-glucosidase activity having IC50 values ranging from 2.40 ± 0.10 to 31.40 ± 0.90 μM and for α-amylase having IC50 values ranging...
Published in: | Chemical Data Collections |
---|---|
Main Author: | Khan S.; Ullah H.; Rahim F.; Taha M.; Hussain R.; Khan M.S.; Ali H.; Khan M.U.; Shah S.A.A.; Khan K.M. |
Format: | Data paper |
Language: | English |
Published: |
Elsevier B.V.
2022
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85142669443&doi=10.1016%2fj.cdc.2022.100967&partnerID=40&md5=3d2e0201d96f4b145daa5366ea80f3bc |
Similar Items
-
Synthesis, in vitro evaluation and molecular docking studies of thiazole derivatives as new inhibitors of α-glucosidase
by: Rahim F.; Ullah H.; Javid M.T.; Wadood A.; Taha M.; Ashraf M.; Shaukat A.; Junaid M.; Hussain S.; Rehman W.; Mehmood R.; Sajid M.; Khan M.N.; Khan K.M.
Published: (2015) -
Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives
by: Khan K.M.; Qurban S.; Salar U.; Taha M.; Hussain S.; Perveen S.; Hameed A.; Ismail N.H.; Riaz M.; Wadood A.
Published: (2016) -
Synthesis, In Vitro α-Amylase Activity, and Molecular Docking Study of New Benzimidazole Derivatives
by: Ullah H.; Ullah H.; Taha M.; Khan F.; Rahim F.; Uddin I.; Sarfraz M.; Shah S.A.A.; Aziz A.; Mubeen S.
Published: (2021) -
New benzoxazole-based sulphonamide hybrids analogs as potent inhibitors of α-amylase and α-glucosidase: Synthesis and in vitro evaluation along with in silico study
by: Khan S.; Rahim F.; Rehman W.; Nawaz M.; Taha M.; Fazil S.; Hussain R.; Adnan Ali Shah S.; Abdellatif M.H.
Published: (2022) -
New triazinoindole bearing thiazole/oxazole analogues: Synthesis, α-amylase inhibitory potential and molecular docking study
by: Rahim F.; Tariq S.; Taha M.; Ullah H.; Zaman K.; Uddin I.; Wadood A.; Khan A.A.; Rehman A.U.; Uddin N.; Zafar S.; Shah S.A.A.
Published: (2019)