New thiazole-based thiazolidinone derivatives: Synthesis, in vitro α-amylase, α-glucosidase activities and silico molecular docking study

A series of thiazole-based thiazolidinone derivatives (1-20) have been synthesized and evaluated against α-glucosidase and α-amylase enzymes. All derivatives showed good α-glucosidase activity having IC50 values ranging from 2.40 ± 0.10 to 31.40 ± 0.90 μM and for α-amylase having IC50 values ranging...

Full description

Bibliographic Details
Published in:Chemical Data Collections
Main Author: Khan S.; Ullah H.; Rahim F.; Taha M.; Hussain R.; Khan M.S.; Ali H.; Khan M.U.; Shah S.A.A.; Khan K.M.
Format: Data paper
Language:English
Published: Elsevier B.V. 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85142669443&doi=10.1016%2fj.cdc.2022.100967&partnerID=40&md5=3d2e0201d96f4b145daa5366ea80f3bc