Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives
Twenty-four analogues of benzimidazole-based thiazoles (1–24) were synthesized and assessed for their in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory potential. All analogues were found to exhibit good inhibitory potential against cholinesterase enzymes, having IC50...
| Published in: | Molecules |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138432376&doi=10.3390%2fmolecules27186087&partnerID=40&md5=00a737ae1c7b971380e00250d596818f |