Efficient Synthesis of 4-Bromo-N-(1-phenylethyl)benzamide, Arylation by Pd(0) Catalyst, Characterization and DFT Study
The (S)-4-bromo-N-(1-phenylethyl)benzamide (3) was synthesized in excellent yield (93 %) by the reaction of 4-bromobenzoic acid (1) and (S)-1-phenylethanamine (2) with the coupling reagent titanium tetrachloride (TiCl4). Further, the Pd(0) catalyst was employed to form (S)-4-bromo-N-(1-phenylethyl)b...
Published in: | ChemistrySelect |
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Main Author: | |
Format: | Article |
Language: | English |
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John Wiley and Sons Inc
2022
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135826802&doi=10.1002%2fslct.202200861&partnerID=40&md5=85c76ec5f31ab2fe11520228935626b1 |