Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations

Breast cancer is the leading cause of cancer-related deaths in women. The aggressive breast cancer subtype is commonly linked to the genetic alterations in the TP53 tumor suppressor gene, predominantly the missense mutations. Robust experimental models are needed to gain better insights into these m...

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Bibliographic Details
Published in:Cells
Main Author: Abuhamad A.Y.; Mohamad Zamberi N.N.; Sheen L.; Naes S.M.; Mohd Yusuf S.N.H.; Ahmad Tajudin A.; Mohtar M.A.; Amir Hamzah A.S.; Syafruddin S.E.
Format: Article
Language:English
Published: MDPI 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129759011&doi=10.3390%2fcells11101612&partnerID=40&md5=68c9b4c1a942d499b9f16d99718a8d01