Synthesis of novel N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-{[5-(un/substituted-phenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamides as potent antibacterial agents

The synthetic methodology was initiated by reacting 1,4-benzodioxane-6-amine (1) with 2-bromoacetyl bromide (2) in aqueous alkaline media under dynamic pH control to get compound 2,3-dihydro-1,4-benzodioxin-6-yl-2-bromoacetamide (3). In the subsequent reactions, a variety of un/substituted-benzoic a...

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Bibliographic Details
Published in:Pakistan Journal of Pharmaceutical Sciences
Main Author: Abbasi M.A.; Irshad M.; Aziz-Ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Shahid M.
Format: Article
Language:English
Published: Pakistan Journal of Pharmaceutical Sciences 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129100563&doi=10.36721%2fPJPS.2022.35.2.REG.447-456.1&partnerID=40&md5=3fccf1b8623d4db94192abdef8f91547