Multi-step synthesis of indole-N-ethyltriazole hybrids amalgamated with N-arylated ethanamides: structure-activity relationship and mechanistic explorations through tyrosinase inhibition, kinetics and computational ascriptions

In the study presented here, novel bioactive series of indole-N-ethyltriazole hybrids was synthesized and structures of these hybrid molecules (9a-h) were corroborated by IR, 1H-NMR, 13C-NMR, EI-MS and CHN analysis data. The in vitro studies of these multi-functional molecules demonstrated their pot...

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Bibliographic Details
Published in:Journal of Molecular Structure
Main Author: Shakila; Abbasi M.A.; Aziz-ur-Rehman; Siddiqui S.Z.; Nazir M.; Raza H.; Zafar A.; Shah S.A.A.; Shahid M.; Seo S.-Y.
Format: Article
Language:English
Published: Elsevier B.V. 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127463628&doi=10.1016%2fj.molstruc.2022.132953&partnerID=40&md5=a567d0d1dd7289e4bc0c51a9dcf8ddab