Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1

QR Code

Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1

Burkholderiapseudomallei lethal factor 1 (BLF1) exhibits site-specific glutamine deamidase activity against the eukaryotic RNA helicase, eIF4A, thereby blocking mammalian protein synthesis. The structure of a complex between BLF1 C94S and human eIF4A shows that the toxin binds in the cleft between t...

Full description

Bibliographic Details
Published in:	Communications Biology
Main Author:	Mobbs G.W.; Aziz A.A.; Dix S.R.; Blackburn G.M.; Sedelnikova S.E.; Minshull T.C.; Dickman M.J.; Baker P.J.; Nathan S.; Raih M.F.; Rice D.W.
Format:	Article
Language:	English
Published:	Nature Research 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127296518&doi=10.1038%2fs42003-022-03186-2&partnerID=40&md5=42193cdc9b8ebc9e5ae18aa38e51237d

Similar Items

The Comprehensive Study on Effective Concentration (EC50) of Antioxidant Activities and Brine Shrimp Lethality of Moringa oleifera
by: Naim Azhar M.A.; Shahimi S.; Abdul Muttalib S.A.
Published: (2024)

Phylogeny and infrageneric classification of Correa Andrews (Rutaceae) on the basis of nuclear and chloroplast DNA
by: Othman R.N.A.; Jordan G.J.; Worth J.R.P.; Steane D.A.; Duretto M.F.
Published: (2010)

The physical and cultural attributes of ethnic enclave: A basis for conservation
by: Bakri A.F.; Qamaruz Zaman N.; Kamarudin H.; Mohd Dom M.; Alias Z.
Published: (2014)

Photocatalysis for organic wastewater treatment: From the basis to current challenges for society
by: Mashuri S.I.S.; Ibrahim M.L.; Kasim M.F.; Mastuli M.S.; Rashid U.; Abdullah A.H.; Islam A.; Asikin-Mijan N.; Tan Y.H.; Mansir N.; Kaus N.H.M.; Hin T.-Y.Y.
Published: (2020)

Graduate Data Job Classification Using Support Vector Machine with Radial Basis Function Kernel
by: Hisham M.H.H.; Abdul Aziz M.A.; Sulaiman A.A.
Published: (2023)

Identification of essential oil extraction system using Radial Basis Function (RBF) Neural Network
by: Yunan I.; Yassin I.M.; Adnan S.F.S.; Rahiman M.H.F.
Published: (2012)

Basis Set Effects on the Stabilities and Interaction Energies of Small Amide Molecules Adsorbed on Kaolinite Surface
by: Nabil N.-A.M.; Ang L.S.; Sulaiman S.
Published: (2023)

Identification of DC motor drive system model using Radial Basis Function (RBF) neural network
by: Yassin I.M.; Taib M.N.; Abdul Aziz M.Z.; Abdul Rahim N.; Tahir N.Md.; Johari A.
Published: (2011)

SCIENTIFIC APPROACH AS THE BASIS FOR THE FORMATION OF MAQĀṢID AL-SHARĪ‘AH CONCEPT AND PRINCIPLES: A COMPARATIVE STUDY
by: Alias M.N.; Abdullah M.N.; Kamis M.S.; Afandi A.J.; Alias N.
Published: (2024)

Performance evaluation of radial basis function (RBF) and multilayer perceptron (MLP) in identifying the contributory factors of learning habits during COVID-19
by: Mangshor N.N.A.; Ibrahim S.; Sabri N.; Hamzah H.H.M.; Kamaruddin S.A.
Published: (2024)

A Learning Design Strategy to Develop a Course for Learning at Scale: A Conceptual Framework for a University-Wide Implementation
by: Ayub E.; Mohamad S.N.A.; Wei G.W.; Luaran J.E.
Published: (2021)

Estimating feature extraction changes of Berkelah Forest, Malaysia from multisensor remote sensing data using and object-based technique
by: Rozali S.; Abd Latif Z.; Adnan N.A.; Hussin Y.; Blackburn A.; Pradhan B.
Published: (2022)

Hypertension Prediction in Adolescents Using Anthropometric Measurements: Do Machine Learning Models Perform Equally Well?
by: Chai S.S.; Goh K.L.; Cheah W.L.; Chang Y.H.R.; Ng G.W.
Published: (2022)

Moderating Students’ Attitudes between Communication, Creation and Information Skills with Perceived Digital Competency
by: Razak N.A.; Seriandi G.; Mien M.; Faizal A.F.; Yin J.G.X.; Lim L.Z.; Nathan V.A.L.
Published: (2024)

XPS/NEXAFS spectroscopic and conductance studies of glycine on AlGaN/GaN transistor devices
by: Myers M.; Khir F.L.M.; Home M.A.; Mennell C.; Gillbanks J.; Tadich A.; Baker M.V.; Nener B.D.; Parish G.
Published: (2018)

Role of GaN cap layer for reference electrode free AlGaN/GaN-based pH sensors
by: Parish G.; Khir F.L.M.; Krishnan N.R.; Wang J.; Krisjanto J.S.; Li H.; Umana-Membreno G.A.; Keller S.; Mishra U.K.; Baker M.V.; Nener B.D.; Myers M.
Published: (2019)

Superhydrophobic coating of silica with photoluminescence properties synthesized from rice husk ash
by: Junaidi M.U.M.; Azaman S.A.H.; Ahmad N.N.R.; Leo C.P.; Lim G.W.; Chan D.J.C.; Yee H.M.
Published: (2017)

Convolutional neural network for solid waste segregation and management
by: Ong T.C.; Yong M.G.O.; Manap N.A.; Abdullah F.; Ong T.S.
Published: (2020)

A multispectral bayesian classification method for increased acoustic discrimination of seabed sediments using multi-frequency multibeam backscatter data
by: Gaida T.C.; Ali T.A.T.; Snellen M.; Amiri-Simkooei A.; van Dijk T.A.G.P.; Simons D.G.
Published: (2018)

Novel Approach to Predict Ground-Level Ozone Concentration Using S-estimation and MM-Estimimation
by: Ul-Saufie A.Z.; Al-Jumeily D.; Hussain A.; Muhamad M.; Musafina J.; Ghali F.; Baker T.
Published: (2020)

Navigating care: family information needs and responsibilities in the context of schizophrenia caregiving
by: Fitryasari R.; Nurlela L.; Syadiyah H.; Yusuf A.; Maliah I.; Ambarwati G.A.; Mulud Z.A.; Diba R.F.; Sari D.W.
Published: (2024)

Molecular structural characteristics that influence partitioning of xenobiotics into human breast milk
by: Agatonovic-Kustrin S.; Morton D.W.
Published: (2015)

Barriers and challenges of implementing pulmonary rehabilitation in Malaysia: Stakeholders’ perspectives
by: Chan S.C.; Sekhon J.K.; Engkasan J.P.; Nathan J.J.; Mirza F.T.; Liew S.M.; Hussein N.; Suhaimi A.; Hanafi N.S.; Pang Y.K.; Yatim S.M.; Jackson T.; Fernandes G.; Habib G.M.M.; Pinnock H.; Khoo E.M.
Published: (2021)

Feasibility, safety and clinical efficiency of optometric service pathways at primary and tertiary care level in ampang, malaysia: A pilot study
by: Hussin D.A.; Hendicott P.; Carkeet A.; Baker P.; Chen A.-H.; Asnir Z.Z.; Abidin Z.Z.; Hussain R.; Mokhtar A.
Published: (2018)

The emergence of Acinetobacter baumannii ST-6 multidrug resistant: A resilient biofilm producer, Malaysia
by: Nathan J.J.; Desa M.N.M.; Yong V.C.; Navaratnam P.; Palanisamy N.K.; Wong E.H.
Published: (2016)

Scientometrics of climate change and shrimp diseases: An overview
by: Bakar K.; Zakariah M.I.; Noor M.I.M.; Ghaffar M.A.; Azra M.N.; Segaran T.C.; Ariffin H.; Téllez-Isaías G.; Kari Z.A.; Bottje W.G.
Published: (2024)

Availability and prioritisation of COVID-19 vaccines among patients with advanced chronic kidney disease and kidney failure during the height of the pandemic: A global survey by the International Society of Nephrology
by: Wijewickrama E.S.; Abdul Hafidz M.I.; Robinson B.M.; Johnson D.W.; Liew A.; Dreyer G.; Caskey F.J.; Bello A.K.; Zaidi D.; Damster S.; Salaro S.; Luyckx V.A.; Bajpai D.
Published: (2022)

High-performance thin-layer chromatographic methods in the evaluation of the antioxidant and anti-hyperglycemic activity of Myrmecodia platytyrea as a promising opportunity in diabetes treatment
by: Agatonovic-Kustrin S.; Morton D.W.; Adam A.; Mizaton H.H.; Zakaria H.
Published: (2017)

A Conducting polymer with enhanced electronic stability applied in cardiac models
by: Mawad D.; Mansfield C.; Lauto A.; Perbellini F.; Nelson G.W.; Tonkin J.; Bello S.O.; Carrad D.J.; Micolich A.P.; Mahat M.M.; Furman J.; Payne D.J.; Lyon A.R.; Gooding J.J.; Harding S.E.; Terracciano C.M.; Stevens M.M.
Published: (2016)

Antifungal and antibiofilm activity of Persian shallot (Allium stipitatum Regel.) against clinically significant candida spp.
by: Karunanidhi A.; Ghaznavi-Rad E.; Nathan J.J.; Fauzi F.M.; Than L.T.L.; Pichika M.R.; Hamat R.A.; Neela V.
Published: (2018)

Bacterial community profiles within the water samples of leptospirosis outbreak areas
by: Md Lasim A.; Mohd Ngesom A.M.; Nathan S.; Abdul Razak F.; Abdul Halim M.; Mohd-Saleh W.; Zainul Abidin K.; Mohd-Taib F.S.
Published: (2024)

Identification of Palmprint Creases Line Equations Features by using Matrix Approach for Individual Profiling
by: Harun N.; Nasir M.A.S.; Aliman S.; Othman P.J.
Published: (2021)

AN ANALYTICAL STUDY OF AWARENESS ABOUT CATARACTS AND VISUAL IMPAIRMENT AMONG UNIVERSITY STUDENTS
by: Saffei N.S.; Ibrahim W.N.A.; Woi P.J.
Published: (2023)

Real-Time Crack Classification with Wall-Climbing Robot Using MobileNetV2
by: Mazni M.; Husain A.R.; Shapiai M.I.; Ibrahim I.S.; Zulkifli R.; Anggara D.W.
Published: (2024)

An investigation into real-time surface crack classification and measurement for structural health monitoring using transfer learning convolutional neural networks and Otsu method
by: Mazni M.; Husain A.R.; Shapiai M.I.; Ibrahim I.S.; Anggara D.W.; Zulkifli R.
Published: (2024)

Identification of Concrete Cracks Using Deep Learning Models: A Systematic Review
by: Mazni M.; Husain A.R.; Shapiai M.I.; Ibrahim I.S.; Zulkifli R.; Anggara D.W.
Published: (2024)

Applying the WHO INSPIRE Framework to Ending Violence Against Pregnant Women and Unborn Children: A Case Study in Vietnam
by: Do, et al.
Published: (2024)

The influence of surface structure on H4SiO4 sorption and oligomerization on goethite surfaces: An XPS study using goethites differing in morphology
by: Song Y.; Swedlund P.J.; Zou C.; Dol Hamid R.
Published: (2013)

Sequence and functional analyses of Haemophilus spp. genomic islands
by: Juhas M.; Power P.M.; Harding R.M.; Ferguson D.J.P.; Dimopoulou I.D.; Elamin A.R.E.; Mohd-Zain Z.; Hood D.W.; Adegbola R.; Erwin A.; Smith A.; Munson R.S.; Harrison A.; Mansfield L.; Bentley S.; Crook D.W.
Published: (2007)

Environmental adaptations to climate change: A scientometric analysis
by: Aziz N.A.; Azra M.N.; Segaran T.C.; Noor M.I.M.; Sung Y.Y.; Dawood M.A.O.; Ghaffar M.A.; Pau T.M.; Bottje W.G.
Published: (2024)