Synthesis, In Vitro, and In Silico Studies of N-(Substituted-Phenyl)-3-(4-Phenyl-1-Piperazinyl)propanamides as Potent Alkaline Phosphatase Inhibitors

Abstract: In the present research work, a new series of N-(substituted-phenyl)-3-(4-phenyl-1-piperazinyl)propanamides were synthesized. The synthesis was initiated by the coupling of different aromatic amines with 3-bromopropanoyl chloride in aqueous basic medium, to synthesize different electrophil...

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Bibliographic Details
Published in:Russian Journal of Bioorganic Chemistry
Main Author: Abbasi M.A.; Nazir M.; Aziz-ur-Rehman; Siddiqui S.Z.; Raza H.; Zafar A.; Shah S.A.A.; Shahid M.
Format: Article
Language:English
Published: Pleiades journals 2021
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117566596&doi=10.1134%2fS1068162021050186&partnerID=40&md5=84d9a5a04753fd680e94e193cd517c89