Synthesis of new urease enzyme inhibitors as antiulcer drug and computational study

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Synthesis of new urease enzyme inhibitors as antiulcer drug and computational study

In search of potent urease inhibitor indole analogues (1–22) were synthesized and evaluated for their urease inhibitory potential. All analogues (1–22) showed a variable degree of inhibitory interaction potential having IC50 value ranging between 0.60 ± 0.05 to 30.90 ± 0.90 µM when compared with sta...

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Bibliographic Details
Published in:	Journal of Biomolecular Structure and Dynamics
Main Author:	Taha M.; Ismail S.; Imran S.; Almandil N.B.; Alomari M.; Rahim F.; Uddin N.; Hayat S.; Zaman K.; Ibrahim M.; Alghanem B.; Islam I.; Farooq R.K.; Boudjelal M.; Khan K.M.
Format:	Article
Language:	English
Published:	Taylor and Francis Ltd. 2022
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104566360&doi=10.1080%2f07391102.2021.1910072&partnerID=40&md5=a1a8b56d06c008f8f5c02429c5d4bf9a

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