Synthesis of new urease enzyme inhibitors as antiulcer drug and computational study

In search of potent urease inhibitor indole analogues (1–22) were synthesized and evaluated for their urease inhibitory potential. All analogues (1–22) showed a variable degree of inhibitory interaction potential having IC50 value ranging between 0.60 ± 0.05 to 30.90 ± 0.90 µM when compared with sta...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Journal of Biomolecular Structure and Dynamics
المؤلف الرئيسي: Taha M.; Ismail S.; Imran S.; Almandil N.B.; Alomari M.; Rahim F.; Uddin N.; Hayat S.; Zaman K.; Ibrahim M.; Alghanem B.; Islam I.; Farooq R.K.; Boudjelal M.; Khan K.M.
التنسيق: مقال
اللغة:English
منشور في: Taylor and Francis Ltd. 2022
الوصول للمادة أونلاين:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104566360&doi=10.1080%2f07391102.2021.1910072&partnerID=40&md5=a1a8b56d06c008f8f5c02429c5d4bf9a