Synthesis of new urease enzyme inhibitors as antiulcer drug and computational study
In search of potent urease inhibitor indole analogues (1–22) were synthesized and evaluated for their urease inhibitory potential. All analogues (1–22) showed a variable degree of inhibitory interaction potential having IC50 value ranging between 0.60 ± 0.05 to 30.90 ± 0.90 µM when compared with sta...
| Published in: | Journal of Biomolecular Structure and Dynamics |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Taylor and Francis Ltd.
2022
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104566360&doi=10.1080%2f07391102.2021.1910072&partnerID=40&md5=a1a8b56d06c008f8f5c02429c5d4bf9a |