Synthesis of benzimidazole derivatives as potent inhibitors for α-amylase and their molecular docking study in management of type-II diabetes

In the search of potent α-amylase inhibitors, we have synthesized seventeen derivatives of 2-mercaptobenzimidazole bearing sulfonamide (1–17) and evaluated for their α-amylase inhibitory potential. All synthesized compounds display a variable degree of α-amylase activity having IC50 values ranging b...

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書目詳細資料
發表在:Journal of Molecular Structure
主要作者: Hussain S.; Taha M.; Rahim F.; Hayat S.; Zaman K.; Iqbal N.; Selvaraj M.; Sajid M.; Bangesh M.A.; Khan F.; Khan K.M.; Uddin N.; Shah S.A.A.; Ali M.
格式: Article
語言:English
出版: Elsevier B.V. 2021
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101323909&doi=10.1016%2fj.molstruc.2021.130029&partnerID=40&md5=2a3ee29ff71e8775509250548c6f68a0