Synthesis of benzimidazole derivatives as potent inhibitors for α-amylase and their molecular docking study in management of type-II diabetes
In the search of potent α-amylase inhibitors, we have synthesized seventeen derivatives of 2-mercaptobenzimidazole bearing sulfonamide (1–17) and evaluated for their α-amylase inhibitory potential. All synthesized compounds display a variable degree of α-amylase activity having IC50 values ranging b...
| Published in: | Journal of Molecular Structure |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2021
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101323909&doi=10.1016%2fj.molstruc.2021.130029&partnerID=40&md5=2a3ee29ff71e8775509250548c6f68a0 |